NAPLEX

NAPLEX practice questions, page 3 of 6, with answer review and explanations.

Question 11

Which of the following is a side effect of valproic acid?

  1. Gingival hyperplasia
  2. Pancreatitis
  3. Kidney stones
  4. Weight loss
  5. Euphoria

Question 12

A 55-year-old female is receiving chemotherapy for metastatic carcinoma. She threatens to stop her treatment because of severe nausea and vomiting. The oncologist plans to use prochlorperazine to reduce the nausea and vomiting associated with chemotherapeutic agents. What is the mechanism of action of prochlorperazine?

  1. Serotonin 5-HT3 antagonist
  2. Blocking dopamine receptors
  3. Cannabinoids related
  4. Blockage of prostaglandins
  5. H2 receptor antagonist

Question 13

A 27-year-old female with ovarian cancer is undergoing chemotherapy. She develops subsequent renal failure. Which of the following drugs is most likely responsible for this?

  1. Cyclophosphamide
  2. Bleomycin
  3. Cisplatin
  4. Vinblastine
  5. Vincristine

Question 14

Your patient is a 43-year-old male who is experiencing post-operative voiding difficulty after an elective inguinal hernia repair. His post void residual volume was 280 cc. Which of the following medications is the most appropriate choice of therapy for this patient?

  1. Bethanechol
  2. Oxybutynin
  3. Phenylephrine
  4. Finasteride
  5. Imipramine

Question 15

Which of the following statements is true regarding Drug-receptor bonds?

  1. Covalent bonds of drugs with receptors are strong and mostly reversible
  2. Covalent bonding is much more common than electrostatic bonding in drug-receptor interactions
  3. Electrostatic bonds are stronger than covalent bonds
  4. Hydrophobic bonds are weak bonds and they are important in the interactions of highly water soluble drugs with the lipids of cell membranes
  5. Bond formation of between the acetyl group of aspirin and cyclo-oxygenase enzyme is a covalent bond